Dr. Muenduen Phisalaphong

ดร. เหมือนเดือน พิศาลพงศ์

Education : Ph.D (Chemical Engineering), Colorado State University, USA, 1996-1999 M.Sc (Chemical Engineering), Lehigh University, USA, 1994-1996 B.Sc (Biotechnology), Kasetsart University, Thailand, 1982-1986


Department of Chemical Engineering, 10th Floor, Building 4,
Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand




Research interest

My research focuses on the natural polymer processing and surface modification. Research interest includes technologies/processes for the development of biomaterials/biopolymer composites for applications in biomedical areas, green catalysis, agriculture, packaging and electronics.


  • Natural polymer processing and surface modification
  • Nano-cellulose based biomaterials
  • Natural rubber composites
  • Activated carbon from bacterial cellulose as an effective adsorbents and catalyst supports
  • Biofuel processing technologies


Biochemical engineering



Biopolymer composites


Chiaoprakobkij, N., Seetabhawang, S., Okhawilai, M., Uyama, H., Phisalaphong, M. Multifunctional bacterial cellulose-gelatin containing mangosteen extract films with improved antibacterial and anticancer properties, 2022, Cellulose, 29 (12), 6811-6830.

Kirdponpattara, S., Chuetor, S., Sriariyanun, M., Phisalaphong, M. Bioethanol Production by Pichia stipitis Immobilized on Water Hyacinth and Thin-shell Silk Cocoon, 2022, Applied Science and Engineering Progress, 15 (3), 4662.

Phomrak, S., Phisalaphong, M., Zhang Newby, B.-M. Surface Wettability of Cellulose Sponges on Effective Oil Uptake, 2022, ACS Applied Bio Materials, 5 (6), 2622-2632.

Phatchayawat, P.P., Khamkeaw, A., Yodmuang, S., Phisalaphong, M. 3D bacterial cellulose-chitosan-alginate-gelatin hydrogel scaffold for cartilage tissue engineering, 2022, Biochemical Engineering Journal, 184, 108476.

Khamkeaw, A., Jongsomjit, B., Yip, A.C.K., Phisalaphong, M. Application of activated carbon derived from bacterial cellulose for mesoporous HZSM-5 catalyst synthesis and performances of catalyst in bioethanol dehydration, 2022, Biomass and Bioenergy, 160, 106440.

Sintharm, P., Nimpaiboon, A., Liao, Y.-C., Phisalaphong, M. Bacterial cellulose reinforced with skim/fresh natural rubber latex for improved mechanical, chemical and dielectric properties, 2022, Cellulose, 29 (3), 1739-1758.

Suttasattakrit, K., Khamkeaw, A., Tangwongsan, C., Pavasant, P., Phisalaphong, M. Ionic silver and electrical treatment for susceptibility and disinfection of escherichia coli biofilm-contaminated titanium surface, 2022, Molecules, 27 (1), 180.

Supanakorn, G., Taokaew, S., Phisalaphong, M. Ternary composite films of natural rubber, cellulose microfiber, and carboxymethyl cellulose for excellent mechanical properties, biodegradability and chemical resistance, 2021, Cellulose 28(13), 8553-8566.

Pisitpaibool, S., Sukrong, S., Kanjanaprapakul, K., Phisalaphong, M. Effects of preharvest methyl jasmonate elicitation and electrical stimulation on camptothecin production by in vitro plants of ophiorrhiza ridleyana craib, 2021, Applied Sciences (Switzerland) 11(10), 4555.

Sintharm, P., Phisalaphong, M. Green natural rubber composites reinforced with black/white rice husk ashes: Effects of reinforcing agent on film’s mechanical and dielectric properties, 2021, Polymers 13(6), 882.

Supanakorn, G., Varatkowpairote, N., Taokaew, S., Phisalaphong, M. Alginate as dispersing agent for compounding natural rubber with high loading microfibrillated cellulose, 2021, Polymers 13(3), 468, 1-11.

Taokaew, S., Chiaoprakobkij, N., Siripong, P., Sanchavanakit, N., Pavasant, P., Phisalaphong, M. Multifunctional cellulosic nanofiber film with enhanced antimicrobial and anticancer properties by incorporation of ethanolic extract of Garcinia mangostana peel, 2021, Materials Science and Engineering C 120, 111783.

Li, R.| Pan, Y.| Li, N.| Wang, Q.| Chen, Y.| Phisalaphong, M.| Chen, H. Corrigendum to “Antibacterial and cytotoxic activities of a green synthesized silver nanoparticles using corn silk aqueous extract” [Colloids Surf. A 598 (2020) 124827] (Colloids and Surfaces A: Physicochemical and Engineering Aspects (2020) 598, (S0927775720304209), (10.1016/j.colsurfa.2020.124827)), 2020, Colloids and Surfaces A: Physicochemical and Engineering Aspects 601, 125165.

Yingyuen, P.| Sukrong, S.| Phisalaphong, M. Isolation, separation and purification of rutin from Banana leaves (Musa balbisiana), 2020, Industrial Crops and Products 149, 112307.

Phomrak, S.| Nimpaiboon, A.| Newby, B.-M.Z.| Phisalaphong, M. Natural rubber latex foam reinforced with micro-and nanofibrillated cellulose via dunlop method, 2020, Polymers 12(9), 1959.

Chen, Y., Wang, Y., Xu, L., Jia, Y., Xue, Z., Zhang, M., Phisalaphong, M., Chen, H. Ultrasound-assisted modified pectin from unripe fruit pomace of raspberry (Rubus chingii Hu): Structural characterization and antioxidant activities, 2020, LWT 134, 110007.

Khamkeaw, A.Asavamongkolkul, T.Perngyai, T.Jongsomjit, B.Phisalaphong, M. Interconnected micro, meso, and macro porous activated carbon from bacterial nanocellulose for superior adsorption properties and effective catalytic performance , 2020,  Molecules, 25(18), 4063.

Chiaoprakobkij, N.Suwanmajo, T.Sanchavanakit, N.Phisalaphong, M.  Curcumin-Loaded Bacterial Cellulose/Alginate/Gelatin as A Multifunctional Biopolymer Composite Film, 2020, Molecules, 25(17), 3800.


Phongphut, A., Chayasombat, B., E.G. Cass, A., Sirisuk, A., Phisalaphong, M., Prichanont, S., Thanachayanont, C. Clay/au nanoparticle composites as acetylcholinesterase carriers and modified-electrode materials: A comparative study, 2020, Applied Clay Science 194, 105704.

Li, R., Pan, Y., Li, N., Wang, Q., Chen, Y., Phisalaphong, M., Chen, H. Antibacterial and cytotoxic activities of a green synthesized silver nanoparticles using corn silk aqueous extract, 2020, Colloids and Surfaces A: Physicochemical and Engineering Aspects 598, 124827.

Yingyuen, P.Sukrong, S.Phisalaphong, M.  Isolation, separation and purification of rutin from Banana leaves (Musa balbisiana), 2020, Industrial Crops and Products 149, 112307.

Phomrak, S.Phisalaphong, M. Lactic acid modified natural rubber-bacterial cellulose composites, 2020, Applied Sciences, 10(10), 3583.

Khamkeaw, A., Phisalaphong, M., Jongsomjit, B., Lin, K. Y. A., Yip, A. C. Synthesis of mesoporous MFI zeolite via bacterial cellulose-derived carbon templating for fast adsorption of formaldehyde. 2020. Journal of hazardous materials, 384, 121161.

Gao X., Santhanam R.K., Xue Z., Jia Y., Wang Y., Lu Y., Phisalaphong M., Chen H. Antioxidant, α-amylase and α-glucosidase activity of various solvent fractions of I. obliquus and the preventive role of active fraction against H2O2 induced damage in hepatic L02 cells as fungisome. (2020). Journal of Food Science.

Khamkeaw, A., Jongsomjit, B., Robison, J., & Phisalaphong, M. Activated carbon from bacterial cellulose as an effective adsorbent for removing dye from aqueous solution. 2019. Separation Science and Technology, 54 (14), 2180-2193.

Khamkeaw, A., Phanthang, L., Jongsomjit, B., Phisalaphong, M. Activated carbon derived from bacterial cellulose and its use as catalyst support for ethanol conversion to ethylene. 2019. Catalysis Communications, 129, 105750.

Chiaoprakobkij, N., Seetabhawang, S., Sanchavanakit, N., Phisalaphong, M. Fabrication and characterization of novel bacterial cellulose/alginate/gelatin biocomposite film. 2019. Journal of Biomaterials Science, Polymer Edition, 30 (11), 961-982.

Potivara, K., Phisalaphong, M. Development and Characterization of Bacterial Cellulose Reinforced with Natural Rubber. 2019.Materials, 12(14), 2323.

Tisarum, R., Theerawitaya, C., Samphumphuang, T., Phisalaphong, M., Singh, H. P., Cha-um, S. Promoting water deficit tolerance and anthocyanin fortification in pigmented rice cultivar (Oryza sativa L. subsp. indica) using arbuscular mycorrhizal fungi inoculation. 2019. Physiology and Molecular Biology of Plants, 25 (4), 821-835.

Panitchakarn, P., Wikranvanich, J., Phisalaphong, M. Synthesis and characterization of natural rubber/coal fly ash composites via latex aqueous microdispersion. 2019. Journal of Material Cycles and Waste Management, 21 (1), 134-144.

Yooyongwech, S., Suriyan, C. U., Tisarum, R., Therawitaya, C., Samphumphung, T., Aumtong, S., Phisalaphong, M. Influence of Different Encapsulation Types of Arbuscular Mycorrhizal Fungi on Physiological Adaptation and Growth Promotion of Maize (Zea mays L.) Subjected to Water Deficit. 2019. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 47 (1), 213-220.

Taokaew, S., Phisalaphong, M. Fabrication of Gelatin Complexes/Bio-Nanocellulose Nanostructured Composite Mats. 2018. In Materials Science Forum (Vol. 936, pp. 142-147). Trans Tech Publications Ltd.

Subtaweesin, C., Woraharn, W., Taokaew, S., Chiaoprakobkij, N., Sereemaspun, A., & Phisalaphong, M. Characteristics of curcumin-loaded bacterial cellulose films and anticancer properties against malignant melanoma skin cancer cells. 2018. Applied Sciences, 8 (7), 1188.

Pitaktamrong, P., Kingkaew, J., Yooyongwech, S., Cha-um, S., Phisalaphong, M. Development of Arbuscular Mycorrhizal Fungi-Organic Fertilizer Pellets Encapsulated with Alginate Film. 2018. Engineering Journal, 22 (6), 65-79.

Khamkeaw, A., Phisalaphong, M. Hydrolysis of cassava starch by co-immobilized multi-microorganisms of Loog-Pang (Thai rice cake starter) for ethanol fermentation. 2016. Food Science and Biotechnology 25 (2) , 509-516.

Boongate, C., Phisalaphong, M. Activated carbons from bacterial cellulose by chemical activation with potassium hydroxide. 2015. Proceedings 2015 International Conference on Science and Technology, TICST 2015 , 144-147.

Mulalee, S., Srisuwan, P., Phisalaphong, M. Influences of operating conditions on biocatalytic activity and reusability of Novozym 435 for esterification of free fatty acids with short-chain alcohols: A case study of palm fatty acid distillate. 2015. Chinese Journal of Chemical Engineering 23 (11) , 1851-1856.

Kirdponpattara, S., Khamkeaw, A., Sanchavanakit, N., Pavasant, P., Phisalaphong, M. Structural modification and characterization of bacterial cellulose-alginate composite scaffolds for tissue engineering. 2015. Carbohydrate Polymers 132 , 146-155.

Kittithanesuan, N., Phisalaphong, M. Enhanced acetone-butanol production from sugarcane juice by immobilized Clostridium acetobutylicum (ATCC 824) on thin-shell silk cocoons. 2015. Biotechnology and Bioprocess Engineering 20 (3) , 599-607.

Taokaew, S., Phisalaphong, M., Newby, B. Modification of bacterial cellulose with organosilanes to improve attachment and spreading of human fibroblasts. 2015. Cellulose 22 (4) , 2311-2324.

Suratago, T., Taokaew, S., Kanjanamosit, N., Kanjanaprapakul, K., Burapatana, V., Phisalaphong, M. Development of bacterial cellulose/alginate nanocomposite membrane for separation of ethanol-water mixtures. 2015. Journal of Industrial and Engineering Chemistry 32 , 305-312.

Taokaew, S., Nunkaew, N., Siripong, P., Phisalaphong, M. Characteristics and anticancer properties of bacterial cellulose films containing ethanolic extract of mangosteen peel. 2014. Journal of Biomaterials Science, Polymer Edition 25 (9) , 907-922.

Taokaew, S., Phisalaphong, M., Zhang Newby, B. In vitro behaviors of rat mesenchymal stem cells on bacterial celluloses with different moduli. 2014. Materials Science and Engineering C 38 (1) , 263-271.

Kingkaew, J., Kirdponpattara, S., Sanchavanakit, N., Pavasant, P., Phisalaphong, M. Effect of molecular weight of chitosan on antimicrobial properties and tissue compatibility of chitosan-impregnated bacterial cellulose films. 2014. 

Biotechnology and Bioprocess Engineering 19 (3) , 534-544.

Kirdponpattara, S., Newby, B., Phisalaphong, M. Effect of oxygen plasma treatment on bacterial cellulose-alginate composite sponge as a yeast cell carrier for ethanol fermentation. 2013. Advanced Materials Research 724-725 , 1150-1153.

Mulalee, S., Chanprasert, J., Kerdpoksup, P., Sawangpanya, N., Phisalaphong, M. Esterification of oleic acid and bioalcohols using immobilized lipase. 2013. Advanced Materials Research 724-725 , 1154-1157.

Kirdponpattara, S., Phisalaphong, M. Bacterial cellulose-alginate composite sponge as a yeast cell carrier for ethanol production. 2013. Biochemical Engineering Journal 77 , 103-109.

Kirdponpattara, S., Phisalaphong, M., Newby, B. Applicability of Washburn capillary rise for determining contact angles of powders/porous materials. 2013. Journal of Colloid and Interface Science 397 , 169-176.

Taokaew, S., Seetabhawang, S., Siripong, P., Phisalaphong, M. Biosynthesis and characterization of nanocellulose-gelatin films. 2013. Materials 6 (3) , 782-794.

Eiadpum, A., Limtong, S., Phisalaphong, M. High-temperature ethanol fermentation by immobilized coculture of Kluyveromyces marxianus and Saccharomyces cerevisiae. 2012. Journal of Bioscience and Bioengineering 114 (3) , 325-329.

Rattanapan, A., Limtong, S., Phisalaphong, M. Ethanol production by repeated batch and continuous fermentations of blackstrap molasses using immobilized yeast cells on thin-shell silk cocoons. 2011. Applied Energy 88 (12) , 4400-4404.

Mongkolkajit, J., Pullsirisombat, J., Limtong, S., Phisalaphong, M. Alumina-doped alginate gel as a cell carrier for ethanol production in a packed-bed bioreactor. 2011. Biotechnology and Bioprocess Engineering 16 (3) , 505-512.

Chiaoprakobkij, N., Sanchavanakit, N., Subbalekha, K., Pavasant, P., Phisalaphong, M. Characterization and biocompatibility of bacterial cellulose/alginate composite

sponges with human keratinocytes and gingival fibroblasts. 2011. Carbohydrate Polymers 85 (3) , 548-553.

Kanjanamosit, N., Muangnapoh, C., Phisalaphong, M. Biosynthesis and characterization of bacteria cellulose-alginate film. 2010. Journal of Applied Polymer Science 115 (3) , 1581-1588.

Kingkaew, J., Jatupaiboon, N., Sanchavanakit, N., Pavasant, P., Phisalaphong, M. Biocompatibility and growth of human keratinocytes and fibroblasts on biosynthesized cellulose-chitosan film. 2010. Journal of Biomaterials Science, Polymer Edition 21 (8-9) , 1009-1021.

Saibuatong, O., Phisalaphong, M. Novo aloe vera-bacterial cellulose composite film from biosynthesis. 2010. Carbohydrate Polymers 79 (2) , 455-460.

Phisalaphong, M., Jatupaiboon, N. Biosynthesis and characterization of bacteria cellulose-chitosan film. 2008. Carbohydrate Polymers 74 (3) , 482-488.

Boonkird, S., Phisalaphong, C., Phisalaphong, M. Ultrasound-assisted extraction of capsaicinoids from Capsicum frutescens on a lab- and pilot-plant scale. 2008. Ultrasonics Sonochemistry 15 (6) , 1075-1079.

Phisalaphong, M., Suwanmajo, T., Tammarate, P. Synthesis and characterization of bacterial cellulose/ alginate blend membranes. 2008. Journal of Applied Polymer Science 107 (5) , 3419-3424.

Phisalaphong, M., Suwanmajo, T., Sangtherapitikul, P. Novel nanoporous membranes from regenerated bacterial cellulose. 2008. Journal of Applied Polymer Science 107 (1) , 292-299.

Phisalaphong, M., Budiraharjo, R., Bangrak, P., Mongkolkajit, J., Limtong, S. Alginate-loofa as carrier matrix for ethanol production. 2007. Journal of Bioscience and Bioengineering 104 (3) , 214-217.

Senger, R., Phisalaphong, M., Karim, M., Linden, J. Development of a culture sub-population induction model: Signaling pathways synergy and taxanes production by Taxus canadensis. 2006. Biotechnology Progress 22 (6) , 1671-1682.

Sanchavanakit, N., Sangrungraungroj, W., Kaomongkolgit, R., Banaprasert, T., Pavasant, P., Phisalaphong, M. Growth of human keratinocytes and fibroblasts on bacterial cellulose film. 2006. Biotechnology Progress 22 (4) , 1194-1199.

Phisalaphong, M., Thu Ha, N., Siripong, P. Desalting of aqueous extract of acanthus ebracteatus Vahl. by nanofiltration. 2006. Separation Science and Technology 41 (3) , 455-470.

Phisalaphong, M., Srirattana, N., Tanthapanichakoon, W. Mathematical modeling to investigate temperature effect on kinetic parameters of ethanol fermentation. 2006. Biochemical Engineering Journal 28 (1) , 36-43.

Linden, J., Phisalaphong, M. Oligosaccharides potentiate methyl jasmonate-induced production of paclitaxel in Taxus canadensis. 2000. Plant Science 158 (1-2) , 41-51.

Phisalaphong, M., Linden, J. Kinetic studies of paclitaxel production by Taxus canadensis cultures in batch and semicontinuous with total cell recycle. 1999. Biotechnology Progress 15 (6) , 1072-1077.